Package: cdtmbnma
Type: Package
Title: Component, Dose, and Time Network Meta-Analysis with
        Dose-Dependent Interactions
Version: 0.2.1
Date: 2026-07-10
Authors@R: 
    person(given = "Tyler", family = "Pitre",
           email = "pitretmed@gmail.com",
           role = c("aut", "cre"))
Description: Bayesian component model-based network meta-analysis for treatment
    combinations with explicit component dose-response and dose-dependent
    interaction surfaces. The main interface fits single-timepoint arm-level
    networks with continuous or binary outcomes, any number of components,
    additive, bilinear, or saturating pairwise interactions, study-level random
    effects, and prediction at unobserved dose combinations. A stage-one
    longitudinal interface fits a two-component exponential time-course model
    with a bilinear interaction on the asymptote. Estimation uses 'Stan' through
    'cmdstanr' or 'rstan'. Methods are described in Welton et al. (2009)
    <doi:10.1093/aje/kwp014>, Mawdsley et al. (2016) <doi:10.1002/psp4.12091>,
    Wicha et al. (2017) <doi:10.1038/s41467-017-01929-y>, and Pedder et al.
    (2019) <doi:10.1002/jrsm.1351>.
License: MIT + file LICENSE
Encoding: UTF-8
Depends: R (>= 4.1.0)
Imports: posterior, stats, graphics, grDevices, utils
Suggests: cmdstanr, rstan, testthat (>= 3.0.0), knitr, rmarkdown, loo
Additional_repositories: https://stan-dev.r-universe.dev
SystemRequirements: A working Stan backend through cmdstanr/CmdStan or
        rstan.
VignetteBuilder: knitr
RoxygenNote: 7.3.2
Config/testthat/edition: 3
NeedsCompilation: no
Packaged: 2026-07-10 12:39:43 UTC; tyler-pitre
Author: Tyler Pitre [aut, cre]
Maintainer: Tyler Pitre <pitretmed@gmail.com>
Repository: CRAN
Date/Publication: 2026-07-22 08:30:21 UTC
Built: R 4.6.1; ; 2026-07-22 12:07:57 UTC; unix
