Package: combiroc
Title: Selection and Ranking of Omics Biomarkers Combinations Made Easy
Date: 2023-07-04
Version: 0.3.4
Language: en-US
Authors@R: 
  c(person(given = "Ivan",
           family = "Ferrari",
           role = "aut",
           email = "ferrari@ingm.org",
           comment = c(ORCID = "0000-0003-3746-4143")),
    person(given = "Riccardo L.",
           family = "Rossi",
           role = c("aut", "cre"),
           email = "ric.rossi@gmail.com",
           comment = c(ORCID = "0000-0002-4964-3264")),
    person(given = "Saveria",
           family = "Mazzara",
           role = "aut",
           email = "saveria.mazzara@gmail.com",
           comment = c(ORCID = "0000-0003-1799-2360")),
    person(given = "Mauro",
           family = "Bombaci",
           role = c("ccp", "ctb", "dtc"),
           email = "bombaci@ingm.org",
           comment = c(ORCID = "0000-0002-9887-4165")))
Description: Provides functions and a workflow to easily and powerfully calculating specificity, sensitivity and ROC curves of biomarkers combinations. Allows to rank and select multi-markers signatures as well as to find the best performing sub-signatures, now also from single-cell RNA-seq datasets. The method used was first published as a Shiny app and described in Mazzara et al. (2017) <doi:10.1038/srep45477> and further described in Bombaci & Rossi (2019) <doi:10.1007/978-1-4939-9164-8_16>, and widely expanded as a package as presented in the bioRxiv pre print Ferrari et al. <doi:10.1101/2022.01.17.476603>.
License: MIT + file LICENSE
Encoding: UTF-8
LazyData: true
RoxygenNote: 7.2.3
Depends: R (>= 3.5.0)
Imports: tidyr, dplyr, ggplot2, gtools, pROC, stringr, stats, utils,
        moments
Suggests: testthat (>= 3.0.0), knitr, markdown, rmarkdown, httr, Seurat
VignetteBuilder: knitr
URL: https://doi.org/10.1101/2022.01.17.476603,
        https://github.com/ingmbioinfo/combiroc
BugReports: https://github.com/ingmbioinfo/combiroc/issues
Config/testthat/edition: 3
NeedsCompilation: no
Packaged: 2023-07-04 10:40:35 UTC; rossiriccardo
Author: Ivan Ferrari [aut] (<https://orcid.org/0000-0003-3746-4143>),
  Riccardo L. Rossi [aut, cre] (<https://orcid.org/0000-0002-4964-3264>),
  Saveria Mazzara [aut] (<https://orcid.org/0000-0003-1799-2360>),
  Mauro Bombaci [ccp, ctb, dtc] (<https://orcid.org/0000-0002-9887-4165>)
Maintainer: Riccardo L. Rossi <ric.rossi@gmail.com>
Repository: CRAN
Date/Publication: 2023-07-06 12:53:12 UTC
Built: R 4.5.2; ; 2025-12-27 03:34:01 UTC; windows
