# Spatiotemporal Mixture Risk Assessment

## Documentation for package ‘GeoTox’ version 1.0.0

- DESCRIPTION file
- User guides, package vignettes and other documentation
- Package NEWS
- Package README

## Help Pages

add_age | Add age simulation data
add_exposure | Add exposure simulation data
add_exposure_rate_params | Add exposure rate simulation data
add_hill_params | Add Hill model parameters
add_obesity | Add obesity simulation data
calc_internal_dose | Calculate internal dose
calc_invitro_concentration | Calculate in vitro concentration
calc_response | Calculate concentrations and risks
calc_risk | Calculate risk scores
calc_sensitivity | Calculate risk sensitivity to a single variable
fit_hill | Fit 2- or 3-parameter Hill model
GeoTox | GeoTox S3 object
geo_tox_data | GeoTox Data
get_assay_table | Get risk metric results
get_boundary | Store and retrieve boundary geometries
get_con | GeoTox S3 object
get_concentration_mean | Get concentration mean values
get_risk_quantiles | Get risk metric results
get_risk_sensitivity | Get risk metric results
get_risk_values | Get risk metric results
sample_simulated_css | Sample from pre-simulated steady-state plasma concentrations
sensitivity_analysis | Perform sensitivity analysis
set_boundary | Store and retrieve boundary geometries
set_fixed_css | Prepare steady-state plasma concentrations for sensitivity analysis
set_sample | Set sample data
set_simulated_css | Set pre-simulated steady-state plasma concentrations
simulate_age | Simulate age values
simulate_exposure | Simulate exposure concentrations
simulate_exposure_rate | Simulate exposure rates
simulate_obesity | Simulate obesity values
simulate_population | Simulate population characteristics and exposures